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pentobarbital will boost the degree or influence of ivosidenib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of ivosidenib with robust CYP3A4 inducers lessened ivosidenib plasma concentrations.pentobarbital will decrease the extent or result of pazopanib by influencing hepatic/inte